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A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade
Neural injury triggers swift responses from glia, including glial migration and phagocytic clearance of damaged neurons. The transcriptional programs governing these complex innate glial immune responses are still unclear. Here, we describe a novel injury assay in adult Drosophila that elicits wides...
Autores principales: | Purice, Maria D, Ray, Arpita, Münzel, Eva Jolanda, Pope, Bernard J, Park, Daniel J, Speese, Sean D, Logan, Mary A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565368/ https://www.ncbi.nlm.nih.gov/pubmed/28825401 http://dx.doi.org/10.7554/eLife.23611 |
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