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The role of desmosomes in carcinogenesis

Desmosomes, which are intercellular adhesive complexes, are essential for the maintenance of epithelial homeostasis. They are located at the cell membrane, where they act as anchors for intermediate filaments. Downregulation of desmosome proteins in various cancers promotes tumor progression. Howeve...

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Detalles Bibliográficos
Autores principales: Zhou, Guangxin, Yang, Linlin, Gray, Ashley, Srivastava, Amit Kumar, Li, Cuiping, Zhang, Gongwen, Cui, Tiantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565390/
https://www.ncbi.nlm.nih.gov/pubmed/28860814
http://dx.doi.org/10.2147/OTT.S136367