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Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and InVitro Efficacy Analysis

JAA-F11 is a highly specific mouse monoclonal to the Thomsen-Friedenreich Antigen (TF-Ag) which is an alpha-O-linked disaccharide antigen on the surface of ~80% of human carcinomas, including breast, lung, colon, bladder, ovarian, and prostate cancers, and is cryptic on normal cells. JAA-F11 has pot...

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Detalles Bibliográficos
Autores principales: Tati, Swetha, Fisk, John C., Abdullah, Julia, Karacosta, Loukia, Chrisikos, Taylor, Philbin, Padraic, Morey, Susan, Ghazal, Diala, Zazala, Fatma, Jessee, Joseph, Quataert, Sally, Koury, Stephen, Moreno, David, Eng, Jing Ying, Glinsky, Vladislav V., Glinskii, Olga V., Sesay, Muctarr, Gebhard, Anthony W., Birthare, Karamveer, Olson, James R., Rittenhouse-Olson, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565633/
https://www.ncbi.nlm.nih.gov/pubmed/28830009
http://dx.doi.org/10.1016/j.neo.2017.07.001