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Carnosine attenuates cyclophosphamide-induced bone marrow suppression by reducing oxidative DNA damage

Oxidative DNA damage in bone marrow cells is the main side effect of chemotherapy drugs including cyclophosphamide (CTX). However, not all antioxidants are effective in inhibiting oxidative DNA damage. In this study, we report the beneficial effect of carnosine (β-alanyl-l-histidine), a special anti...

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Detalles Bibliográficos
Autores principales: Deng, Jie, Zhong, Yi-Fei, Wu, Yan-Ping, Luo, Zhuo, Sun, Yuan-Ming, Wang, Guo-En, Kurihara, Hiroshi, Li, Yi-Fang, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565745/
https://www.ncbi.nlm.nih.gov/pubmed/28826042
http://dx.doi.org/10.1016/j.redox.2017.08.003