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Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux

Energy production is inevitably linked to the generation of toxic metabolites, such as reactive oxygen and carbonyl species, known as major contributors to ageing and degenerative diseases. It remains unclear how cells can adapt to elevated energy flux accompanied by accumulating harmful by-products...

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Detalles Bibliográficos
Autores principales: Zemva, Johanna, Fink, Christoph Andreas, Fleming, Thomas Henry, Schmidt, Leonard, Loft, Anne, Herzig, Stephan, Knieß, Robert André, Mayer, Matthias, Bukau, Bernd, Nawroth, Peter Paul, Tyedmers, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565788/
https://www.ncbi.nlm.nih.gov/pubmed/28826004
http://dx.doi.org/10.1016/j.redox.2017.08.007