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Bcl3: a regulator of NF-κB inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells

Acute kidney injury (AKI) is characterized by tubular cell death and interstitial inflammation. TWEAK promotes experimental kidney injury and activates the transcription factor NF-κB, a key regulator of genes involved in cell survival and inflammatory response. In search of potential therapeutic tar...

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Detalles Bibliográficos
Autores principales: Poveda, Jonay, Sanz, Ana B, Carrasco, Susana, Ruiz-Ortega, Marta, Cannata-Ortiz, Pablo, Sanchez-Niño, Maria D, Ortiz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565957/
https://www.ncbi.nlm.nih.gov/pubmed/28684863
http://dx.doi.org/10.1038/emm.2017.89