MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis

While dispensable for viral replication, coronavirus (CoV) accessory open reading frame (ORF) proteins often play critical roles during infection and pathogenesis. Utilizing a previously generated mutant, we demonstrate that the absence of all four Middle East respiratory syndrome CoV (MERS-CoV) acc...

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Detalles Bibliográficos
Autores principales: Menachery, Vineet D., Mitchell, Hugh D., Cockrell, Adam S., Gralinski, Lisa E., Yount, Boyd L., Graham, Rachel L., McAnarney, Eileen T., Douglas, Madeline G., Scobey, Trevor, Beall, Anne, Dinnon, Kenneth, Kocher, Jacob F., Hale, Andrew E., Stratton, Kelly G., Waters, Katrina M., Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565963/
https://www.ncbi.nlm.nih.gov/pubmed/28830941
http://dx.doi.org/10.1128/mBio.00665-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565963/
https://www.ncbi.nlm.nih.gov/pubmed/28830941
http://dx.doi.org/10.1128/mBio.00665-17

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