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The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane

All enveloped viruses, including herpesviruses, must fuse their envelope with the host membrane to deliver their genomes into target cells, making this essential step subject to interference by antibodies and drugs. Viral fusion is mediated by a viral surface protein that transits from an initial pr...

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Detalles Bibliográficos
Autores principales: Fontana, Juan, Atanasiu, Doina, Saw, Wan Ting, Gallagher, John R., Cox, Reagan G., Whitbeck, J. Charles, Brown, Lauren M., Eisenberg, Roselyn J., Cohen, Gary H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565971/
https://www.ncbi.nlm.nih.gov/pubmed/28830949
http://dx.doi.org/10.1128/mBio.01268-17