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Discovery of Aptamer Ligands for Hepatic Stellate Cells Using SELEX

Insulin like growth factor II receptor (IGFIIR) is a transmembrane protein overexpressed in activated hepatic stellate cells (HSCs), which are the major target for the treatment of liver fibrosis. In this study, we aim to discover an IGFIIR-specific aptamer that can be potentially used as a targetin...

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Detalles Bibliográficos
Autores principales: Chen, Zhijin, Liu, Hao, Jain, Akshay, Zhang, Li, Liu, Chang, Cheng, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566100/
https://www.ncbi.nlm.nih.gov/pubmed/28839458
http://dx.doi.org/10.7150/thno.19374