Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes

Mesoporous silica nanoparticles (MSNs) are extensively explored as drug delivery systems, but in depth understanding of design-toxicity relationships is still scarce. We used zebrafish (Danio rerio) embryos to study toxicity profiles of differently surface functionalized MSNs. Embryos with the chori...

Descripción completa

Detalles Bibliográficos
Autores principales: Paatero, Ilkka, Casals, Eudald, Niemi, Rasmus, Özliseli, Ezgi, Rosenholm, Jessica M., Sahlgren, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566213/
https://www.ncbi.nlm.nih.gov/pubmed/28827674
http://dx.doi.org/10.1038/s41598-017-09312-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566213/
https://www.ncbi.nlm.nih.gov/pubmed/28827674
http://dx.doi.org/10.1038/s41598-017-09312-z

Ejemplares similares