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Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Recent evidence indicates that single multiple sclerosis (MS) susceptibility genes involved in interferon (IFN) signaling display altered transcript levels in peripheral blood of untreated MS subjects, suggesting that responsiveness to endogenous IFN is dysregulated during neuroinflammation. To prov...

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Detalles Bibliográficos
Autores principales: Srinivasan, Sundararajan, Severa, Martina, Rizzo, Fabiana, Menon, Ramesh, Brini, Elena, Mechelli, Rosella, Martinelli, Vittorio, Hertzog, Paul, Salvetti, Marco, Furlan, Roberto, Martino, Gianvito, Comi, Giancarlo, Coccia, Eliana M., Farina, Cinthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566335/
https://www.ncbi.nlm.nih.gov/pubmed/28827704
http://dx.doi.org/10.1038/s41598-017-09286-y