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TDAG8, TRPV1, and ASIC3 involved in establishing hyperalgesic priming in experimental rheumatoid arthritis

Rheumatoid arthritis (RA), characterized by chronic inflammation of synovial joints, is often associated with ongoing pain and increased pain sensitivity. High hydrogen ion concentration (acidosis) found in synovial fluid in RA patients is associated with disease severity. Acidosis signaling acting...

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Detalles Bibliográficos
Autores principales: Hsieh, Wei-Shan, Kung, Chia-Chi, Huang, Shir-Ly, Lin, Shih-Chang, Sun, Wei-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566336/
https://www.ncbi.nlm.nih.gov/pubmed/28827659
http://dx.doi.org/10.1038/s41598-017-09200-6