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Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process

Nonsteroidal 2-arylproprionic acids are widely used, over-the-counter, anti-inflammatory drugs. Photosensitivity is a commonly overlooked adverse effect of these drugs. Based on the combined use of cell viability assays and molecular modeling, we prove and rationalize the photochemical pathways trig...

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Detalles Bibliográficos
Autores principales: Bignon, Emmanuelle, Marazzi, Marco, Besancenot, Vanessa, Gattuso, Hugo, Drouot, Guillaume, Morell, Christophe, Eriksson, Leif A., Grandemange, Stephanie, Dumont, Elise, Monari, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566383/
https://www.ncbi.nlm.nih.gov/pubmed/28827702
http://dx.doi.org/10.1038/s41598-017-09406-8