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Conditional, Genetically Encoded, Small Molecule–Regulated Inhibition of NFκB Signaling in RPE Cells

PURPOSE: Nuclear factor κB (NFκB) is a ubiquitously expressed, proinflammatory transcription factor that controls the expression of genes involved in cell survival, angiogenesis, complement activation, and inflammation. Studies have implicated NFκB-dependent cytokines or complement-related factors a...

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Detalles Bibliográficos
Autores principales: Vu, Khiem T., Zhang, Fang, Hulleman, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566385/
https://www.ncbi.nlm.nih.gov/pubmed/28829844
http://dx.doi.org/10.1167/iovs.17-22133