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Juxtacrine Activity of Estrogen Receptor α in Uterine Stromal Cells is Necessary for Estrogen-Induced Epithelial Cell Proliferation

Aberrant regulation of uterine cell growth can lead to endometrial cancer and infertility. To understand the molecular mechanisms of estrogen-induced uterine cell growth, we removed the estrogen receptor α (Esr1) from mouse uterine stromal cells, where the embryo is implanted during pregnancy. Witho...

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Detalles Bibliográficos
Autores principales: Winuthayanon, Wipawee, Lierz, Sydney L., Delarosa, Karena C., Sampels, Skylar R., Donoghue, Lauren J., Hewitt, Sylvia C., Korach, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566397/
https://www.ncbi.nlm.nih.gov/pubmed/28827707
http://dx.doi.org/10.1038/s41598-017-07728-1