Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism

TAp63, a member of the p53 family, has been shown to regulate energy metabolism. Here, we report coiled coil domain-containing 3 (CCDC3) as a new TAp63 target. TAp63, but not ΔNp63, p53 or p73, upregulates CCDC3 expression by directly binding to its enhancer region. The CCDC3 expression is markedly...

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Detalles Bibliográficos
Autores principales: Liao, Wenjuan, Liu, Hongbing, Zhang, Yiwei, Jung, Ji Hoon, Chen, Jiaxiang, Su, Xiaohua, Kim, Yeong C., Flores, Elsa R, Wang, San Ming, Czarny-Ratajczak, Malwina, Li, Wen, Zeng, Shelya X., Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566403/
https://www.ncbi.nlm.nih.gov/pubmed/28827783
http://dx.doi.org/10.1038/s41598-017-09228-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566403/
https://www.ncbi.nlm.nih.gov/pubmed/28827783
http://dx.doi.org/10.1038/s41598-017-09228-8

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