pH-sensitive and folic acid-targeted MPEG-PHIS/FA-PEG-VE mixed micelles for the delivery of PTX-VE and their antitumor activity

The aim of this study was to simultaneously introduce pH sensitivity and folic acid (FA) targeting into a micelle system to achieve quick drug release and to enhance its accumulation in tumor cells. Paclitaxel-(+)-α-tocopherol (PTX-VE)-loaded mixed micelles (PHIS/FA/PM) fabricated by poly(ethylene g...

Descripción completa

Detalles Bibliográficos
Autores principales: Di, Yan, Li, Ting, Zhu, Zhihong, Chen, Fen, Jia, Lianqun, Liu, Wenbing, Gai, Xiumei, Wang, Yingying, Pan, Weisan, Yang, Xinggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566413/
https://www.ncbi.nlm.nih.gov/pubmed/28860753
http://dx.doi.org/10.2147/IJN.S141982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566413/
https://www.ncbi.nlm.nih.gov/pubmed/28860753
http://dx.doi.org/10.2147/IJN.S141982

Ejemplares similares