Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics

The tamoxifen-inducible Cre system is a popular transgenic method for controlling the induction of recombination by Cre at a specific time and in a specific cell type. However, tamoxifen is not an inert inducer of recombination, but an established endocrine disruptor with mixed agonist/antagonist ac...

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Detalles Bibliográficos
Autores principales: Patel, Saloni H., O’Hara, Laura, Atanassova, Nina, Smith, Sarah E., Curley, Michael K., Rebourcet, Diane, Darbey, Annalucia L., Gannon, Anne-Louise, Sharpe, Richard M., Smith, Lee B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566418/
https://www.ncbi.nlm.nih.gov/pubmed/28827578
http://dx.doi.org/10.1038/s41598-017-09016-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566418/
https://www.ncbi.nlm.nih.gov/pubmed/28827578
http://dx.doi.org/10.1038/s41598-017-09016-4

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