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The Us2 Gene Product of Herpes Simplex Virus 2 modulates NF-κB activation by targeting TAK1

HSV-2 is one of the most common sexually transmitted pathogens worldwide and HSV-2 infection triggers cytokine and chemokine production. However, little is known about which HSV-2 genes engage in the regulation of NF-κB signaling and what mechanisms are involved. In a screen of the unique short (Us)...

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Detalles Bibliográficos
Autores principales: Lu, Xuan, Huang, Changjing, Zhang, Yi, Lin, Yong, Wang, Xueyu, Li, Qian, Liu, Shi, Tang, Jingfeng, Zhou, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566419/
https://www.ncbi.nlm.nih.gov/pubmed/28827540
http://dx.doi.org/10.1038/s41598-017-08856-4