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Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes

Our previous GWAS using samples from the NSABP P-1 and P-2 selective estrogen receptor modulator (SERM) breast cancer prevention trials identified SNPs in ZNF423 and near CTSO that were associated with breast cancer risk during SERM chemoprevention. We have now performed Next Generation DNA sequenci...

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Detalles Bibliográficos
Autores principales: Liu, Duan, Ho, Ming-Fen, Schaid, Daniel J., Scherer, Steven E., Kalari, Krishna, Liu, Mohan, Biernacka, Joanna, Yee, Vivien, Evans, Jared, Carlson, Erin, Goetz, Matthew P., Kubo, Michiaki, Wickerham, D. Lawrence, Wang, Liewei, Ingle, James N., Weinshilboum, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566425/
https://www.ncbi.nlm.nih.gov/pubmed/28856246
http://dx.doi.org/10.1038/s41523-017-0036-4