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Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin

Neuroserpin is a serine protease inhibitor that regulates the activity of plasmin and its activators in the neuronal tissues. This study provides novel evidence of regulatory effect of the neuroserpin on plasmin proteolytic activity in the retina in glaucoma. Human retinal and vitreous tissues from...

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Detalles Bibliográficos
Autores principales: Gupta, Vivek, Mirzaei, Mehdi, Gupta, Veer Bala, Chitranshi, Nitin, Dheer, Yogita, Vander Wall, Roshana, Abbasi, Mojdeh, You, Yuyi, Chung, Roger, Graham, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566433/
https://www.ncbi.nlm.nih.gov/pubmed/28827627
http://dx.doi.org/10.1038/s41598-017-08688-2