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Sensitive genotyping of mutations in the EGFR gene from NSCLC patients using PCR-GoldMag lateral flow device

Epidermal growth factor receptor (EGFR) mutations predict better outcomes with EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer (NSCLC). Most common activating mutations include in-frame deletion in exon 19 and L858R substitution in exon 21, which account for >90% of al...

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Detalles Bibliográficos
Autores principales: Li, Xian-Ying, Zhang, Chao, Zhang, Qin-Lu, Zhu, Juan-Li, Liu, Qian, Chen, Ming-Wei, Yang, Xue-Min, Hui, Wen-Li, Cui, Ya-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566435/
https://www.ncbi.nlm.nih.gov/pubmed/28827701
http://dx.doi.org/10.1038/s41598-017-08210-8