PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway

Cell-mediated contraction of collagenous matrices is modulated by various growth factors and cytokines, such as platelet-derived growth factor-BB (PDGF-BB). Here we used a genetic cell model to delineate defined signaling pathways that enhance collagen gel contraction downstream of ligand-stimulated...

Descripción completa

Detalles Bibliográficos
Autores principales: Reyhani, Vahid, Tsioumpekou, Maria, van Wieringen, Tijs, Rask, Lars, Lennartsson, Johan, Rubin, Kristofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566449/
https://www.ncbi.nlm.nih.gov/pubmed/28827622
http://dx.doi.org/10.1038/s41598-017-08411-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566449/
https://www.ncbi.nlm.nih.gov/pubmed/28827622
http://dx.doi.org/10.1038/s41598-017-08411-1

Ejemplares similares