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PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway

Cell-mediated contraction of collagenous matrices is modulated by various growth factors and cytokines, such as platelet-derived growth factor-BB (PDGF-BB). Here we used a genetic cell model to delineate defined signaling pathways that enhance collagen gel contraction downstream of ligand-stimulated...

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Detalles Bibliográficos
Autores principales:	Reyhani, Vahid, Tsioumpekou, Maria, van Wieringen, Tijs, Rask, Lars, Lennartsson, Johan, Rubin, Kristofer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566449/ https://www.ncbi.nlm.nih.gov/pubmed/28827622 http://dx.doi.org/10.1038/s41598-017-08411-1

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