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Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching
High-throughput single-stranded DNA sequencing (ssDNA-seq) of cell-free DNA from plasma and other bodily fluids is a powerful method for non-invasive prenatal testing, and diagnosis of cancers and other diseases. Here, we developed a facile ssDNA-seq method, which exploits a novel template-switching...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566474/ https://www.ncbi.nlm.nih.gov/pubmed/28827600 http://dx.doi.org/10.1038/s41598-017-09064-w |