Protein structure shapes immunodominance in the CD4 T cell response to yellow fever vaccination

The live attenuated yellow fever (YF) vaccine is a highly effective human vaccine and induces long-term protective neutralizing antibodies directed against the viral envelope protein E. The generation of such antibodies requires the help of CD4 T cells which recognize peptides derived from proteins...

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Detalles Bibliográficos
Autores principales: Koblischke, Maximilian, Mackroth, Maria S., Schwaiger, Julia, Fae, Ingrid, Fischer, Gottfried, Stiasny, Karin, Heinz, Franz X., Aberle, Judith H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566484/
https://www.ncbi.nlm.nih.gov/pubmed/28827760
http://dx.doi.org/10.1038/s41598-017-09331-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566484/
https://www.ncbi.nlm.nih.gov/pubmed/28827760
http://dx.doi.org/10.1038/s41598-017-09331-w

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