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SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
Distant metastasis is the main cause of breast cancer-related death; however, effective therapeutic strategies targeting metastasis are still scarce. This is largely attributable to the spatiotemporal intratumor heterogeneity during metastasis. Here we show that protein deacetylase SIRT7 is signific...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566498/ https://www.ncbi.nlm.nih.gov/pubmed/28827661 http://dx.doi.org/10.1038/s41467-017-00396-9 |