The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion

Fasciola hepatica infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore the responses of CD4 T-cells within the major draining lymph nodes. We found minimal expression of Foxp3 within CD4 cells but...

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Detalles Bibliográficos
Autores principales: Sachdev, Divya, Gough, Kevin C., Flynn, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566560/
https://www.ncbi.nlm.nih.gov/pubmed/28871261
http://dx.doi.org/10.3389/fimmu.2017.01002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566560/
https://www.ncbi.nlm.nih.gov/pubmed/28871261
http://dx.doi.org/10.3389/fimmu.2017.01002

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