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The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion
Fasciola hepatica infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore the responses of CD4 T-cells within the major draining lymph nodes. We found minimal expression of Foxp3 within CD4 cells but...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566560/ https://www.ncbi.nlm.nih.gov/pubmed/28871261 http://dx.doi.org/10.3389/fimmu.2017.01002 |