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Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis

Paracoccidioidomycosis (PCM), a chronic granulomatous disease caused by the thermally dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii, has the highest mortality rate among systemic mycosis. The T helper 1-mediated immunity is primarily responsible for acquired resistance d...

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Detalles Bibliográficos
Autores principales: Tristão, Fabrine Sales Massafera, Rocha, Fernanda Agostini, Carlos, Daniela, Ketelut-Carneiro, Natália, Souza, Camila Oliveira Silva, Milanezi, Cristiane Maria, Silva, João Santana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566564/
https://www.ncbi.nlm.nih.gov/pubmed/28871251
http://dx.doi.org/10.3389/fimmu.2017.00949