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Single-Domain Antibodies As Versatile Affinity Reagents for Analytical and Diagnostic Applications

With just three CDRs in their variable domains, the antigen-binding site of camelid heavy-chain-only antibodies (HcAbs) has a more limited structural diversity than that of conventional antibodies. Even so, this does not seem to limit their specificity and high affinity as HcAbs against a broad rang...

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Detalles Bibliográficos
Autores principales: Gonzalez-Sapienza, Gualberto, Rossotti, Martín A., Tabares-da Rosa, Sofía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566570/
https://www.ncbi.nlm.nih.gov/pubmed/28871254
http://dx.doi.org/10.3389/fimmu.2017.00977