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An Aptamer-Based Biosensor for the Azole Class of Antifungal Drugs

This technical report describes the development of an aptamer for sensing azole antifungal drugs during therapeutic drug monitoring. Modified synthetic evolution of ligands through exponential enrichment (SELEX) was used to discover a DNA aptamer recognizing azole class antifungal drugs. This aptame...

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Detalles Bibliográficos
Autores principales: Wiedman, Gregory R., Zhao, Yanan, Mustaev, Arkady, Ping, Jinglei, Vishnubhotla, Ramya, Johnson, A. T. Charlie, Perlin, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566834/
https://www.ncbi.nlm.nih.gov/pubmed/28861519
http://dx.doi.org/10.1128/mSphere.00274-17