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Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells

Positively charged cyclodextrins (PCCDs) are molecular carriers of particular interest for their ability to readily enter into cancer cells. Of main interest, guanidino- and aminoalkyl- PCCDs can be conveniently synthesized and form stable and strong inclusion complexes with various active molecules...

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Detalles Bibliográficos
Autores principales: Rodriguez-Ruiz, Violeta, Maksimenko, Andrey, Salzano, Giuseppina, Lampropoulou, Maria, Lazarou, Yannis G., Agostoni, Valentina, Couvreur, Patrick, Gref, Ruxandra, Yannakopoulou, Konstantina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566897/
https://www.ncbi.nlm.nih.gov/pubmed/28827534
http://dx.doi.org/10.1038/s41598-017-08727-y