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Human Leukocyte Antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 Present Complementary Peptide Repertoires

Human leukocyte antigen (HLA)-DR15 is a haplotype associated with multiple sclerosis. It contains the two DRB* genes DRB1*1501 (DR2b) and DRB5*0101 (DR2a). The reported anchor motif of the corresponding HLA-DR molecules was determined in 1994 based on a small number of peptide ligands and binding as...

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Detalles Bibliográficos
Autores principales: Scholz, Erika Margaret, Marcilla, Miguel, Daura, Xavier, Arribas-Layton, David, James, Eddie A., Alvarez, Iñaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566978/
https://www.ncbi.nlm.nih.gov/pubmed/28871256
http://dx.doi.org/10.3389/fimmu.2017.00984