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Severe Tuberculosis in Humans Correlates Best with Neutrophil Abundance and Lymphocyte Deficiency and Does Not Correlate with Antigen-Specific CD4 T-Cell Response

It is generally thought that Mycobacterium tuberculosis (Mtb)-specific CD4(+) Th1 cells producing IFN-γ are essential for protection against tuberculosis (TB). In some studies, protection has recently been associated with polyfunctional subpopulation of Mtb-specific Th1 cells, i.e., with cells able...

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Detalles Bibliográficos
Autores principales: Panteleev, Alexander V., Nikitina, Irina Yu, Burmistrova, Irina A., Kosmiadi, George A., Radaeva, Tatyana V., Amansahedov, Rasul B., Sadikov, Pavel V., Serdyuk, Yana V., Larionova, Elena E., Bagdasarian, Tatef R., Chernousova, Larisa N., Ganusov, Vitaly V., Lyadova, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566990/
https://www.ncbi.nlm.nih.gov/pubmed/28871253
http://dx.doi.org/10.3389/fimmu.2017.00963