Next-Generation Sequencing in Order to Better Characterize a BRCA Variant of Uncertain Significance

BRCA germline mutations are the most common predisposing factor in familial breast-ovarian cancer syndrome families. However, many screened patients are identified as harboring BRCA variants of uncertain significance (VUS), rather than carrying deleterious germline mutations [Calo et al.: Cancers 20...

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Detalles Bibliográficos
Autores principales: Sorscher, Steven, Ramkissoon, Shakti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566997/
https://www.ncbi.nlm.nih.gov/pubmed/28868023
http://dx.doi.org/10.1159/000478005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566997/
https://www.ncbi.nlm.nih.gov/pubmed/28868023
http://dx.doi.org/10.1159/000478005

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