Live-cell p53 single-molecule binding is modulated by C-terminal acetylation and correlates with transcriptional activity

Live-cell microscopy has highlighted that transcription factors bind transiently to chromatin but it is not clear if the duration of these binding interactions can be modulated in response to an activation stimulus, and if such modulation can be controlled by post-translational modifications of the...

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Detalles Bibliográficos
Autores principales: Loffreda, Alessia, Jacchetti, Emanuela, Antunes, Sofia, Rainone, Paolo, Daniele, Tiziana, Morisaki, Tatsuya, Bianchi, Marco E., Tacchetti, Carlo, Mazza, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567047/
https://www.ncbi.nlm.nih.gov/pubmed/28827596
http://dx.doi.org/10.1038/s41467-017-00398-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567047/
https://www.ncbi.nlm.nih.gov/pubmed/28827596
http://dx.doi.org/10.1038/s41467-017-00398-7

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