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Combinatory repair strategy to promote axon regeneration and functional recovery after chronic spinal cord injury

Eight weeks post contusive spinal cord injury, we built a peripheral nerve graft bridge (PNG) through the cystic cavity and treated the graft/host interface with acidic fibroblast growth factor (aFGF) and chondroitinase ABC (ChABC). This combinatorial strategy remarkably enhanced integration between...

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Detalles Bibliográficos
Autores principales: DePaul, Marc A., Lin, Ching-Yi, Silver, Jerry, Lee, Yu-Shang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567101/
https://www.ncbi.nlm.nih.gov/pubmed/28827771
http://dx.doi.org/10.1038/s41598-017-09432-6