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T cell specific Cxcr5 deficiency prevents rheumatoid arthritis

The chemokine receptor CXCR5 is primarily expressed on B cells and Tfh cells and facilitates their migration towards B cell follicles. In the present study we investigated the role of the CXCL13/CXCR5 axis in the pathogenesis of rheumatoid arthritis (RA) and specifically addressed the impact of CXCR...

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Detalles Bibliográficos
Autores principales: Moschovakis, Georgios L., Bubke, Anja, Friedrichsen, Michaela, Falk, Christine S., Feederle, Regina, Förster, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567121/
https://www.ncbi.nlm.nih.gov/pubmed/28827539
http://dx.doi.org/10.1038/s41598-017-08935-6