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CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock

Current biomarkers for sepsis are limited by their non-specificity, short half-life, and insensitive response to therapy. Recently, we have demonstrated that citrullinated histone H3(CitH3) is released into the blood from neutrophil extracellular traps(NETs) in response to severe infection, and CitH...

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Detalles Bibliográficos
Autores principales: Pan, Baihong, Alam, Hasan B., Chong, Wei, Mobley, James, Liu, Baoling, Deng, Qiufang, Liang, Yinjian, Wang, Yanming, Chen, Eric, Wang, Tianbing, Tewari, Muneesh, Li, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567134/
https://www.ncbi.nlm.nih.gov/pubmed/28827548
http://dx.doi.org/10.1038/s41598-017-09337-4