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Outer membrane vesicle-associated lipase FtlA enhances cellular invasion and virulence in Francisella tularensis LVS

Francisella tularensis is a highly infectious intracellular pathogen that infects a wide range of host species and causes fatal pneumonic tularemia in humans. ftlA was identified as a potential virulence determinant of the F. tularensis live vaccine strain (LVS) in our previous transposon screen, bu...

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Detalles Bibliográficos
Autores principales: Chen, Fei, Cui, Guolin, Wang, Shuxia, Nair, Manoj Kumar Mohan, He, Lihong, Qi, Xinyi, Han, Xiangmin, Zhang, Hanqi, Zhang, Jing-Ren, Su, Jingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567169/
https://www.ncbi.nlm.nih.gov/pubmed/28745311
http://dx.doi.org/10.1038/emi.2017.53