Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation

After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation. Thus, we tes...

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Detalles Bibliográficos
Autores principales: Zebrowski, David C., Jensen, Charlotte H., Becker, Robert, Ferrazzi, Fulvia, Baun, Christina, Hvidsten, Svend, Sheikh, Søren P., Polizzotti, Brian D., Andersen, Ditte C., Engel, Felix B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567176/
https://www.ncbi.nlm.nih.gov/pubmed/28827644
http://dx.doi.org/10.1038/s41598-017-08947-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567176/
https://www.ncbi.nlm.nih.gov/pubmed/28827644
http://dx.doi.org/10.1038/s41598-017-08947-2

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