Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

Frontotemporal dementia (FTD) is a neurodegenerative disorder predominantly affecting the frontal and temporal lobes. Genome-wide association studies (GWAS) on FTD identified only a few risk loci. One of the possible explanations is that FTD is clinically, pathologically, and genetically heterogeneo...

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Detalles Bibliográficos
Autores principales: Taskesen, E., Mishra, A., van der Sluis, S., Ferrari, R., Veldink, J. H., van Es, M. A., Smit, A. B., Posthuma, D., Pijnenburg, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567187/
https://www.ncbi.nlm.nih.gov/pubmed/28827549
http://dx.doi.org/10.1038/s41598-017-09320-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567187/
https://www.ncbi.nlm.nih.gov/pubmed/28827549
http://dx.doi.org/10.1038/s41598-017-09320-z

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