Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin

Acquired drug resistance poses a great challenge in cancer therapy. Drug efflux and anti-apoptotic processes are the most two common mechanisms that confer cancer drug resistance. In this study, we found that Schisandrin B (Sch B), one of the major dibenzocyclooctadiene derivatives extracted from Ch...

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Detalles Bibliográficos
Autores principales: Wang, Shengpeng, Wang, Anqi, Shao, Min, Lin, Ligen, Li, Peng, Wang, Yitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567212/
https://www.ncbi.nlm.nih.gov/pubmed/28827665
http://dx.doi.org/10.1038/s41598-017-08817-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567212/
https://www.ncbi.nlm.nih.gov/pubmed/28827665
http://dx.doi.org/10.1038/s41598-017-08817-x

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