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Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression

Our recent studies have indicated that specificity protein-1 (Sp1) accumulates substantially in the early stage of lung cancer but is partially decreased in the late stages, which is an important factor in the progression of the cancer. In this study, we found that Nm23-H1 and hnRNPA2/B1 could be re...

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Detalles Bibliográficos
Autores principales: Hung, Chia-Yang, Wang, Yi-Chang, Chuang, Jian-Ying, Young, Ming-Jer, Liaw, Hungjiun, Chang, Wen-Chang, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567229/
https://www.ncbi.nlm.nih.gov/pubmed/28831131
http://dx.doi.org/10.1038/s41598-017-09558-7