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Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis

Non-alcoholic fatty liver disease closely contributes to the development of obesity and insulin resistance. Even though pioglitazone has been reported to effectively lessen hepatic steatosis in human studies, its molecular mechanism remains unclear. This study is designed to investigate the regulati...

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Detalles Bibliográficos
Autores principales: Hsiao, Pi-Jung, Chiou, Hsin-Ying Clair, Jiang, He-Jiun, Lee, Mei-Yueh, Hsieh, Tusty-Jiuan, Kuo, Kung-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567271/
https://www.ncbi.nlm.nih.gov/pubmed/28831172
http://dx.doi.org/10.1038/s41598-017-09702-3