Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity. We recently generated a Plasmodium berghei (PbNK65) parasite that lacks a secreted factor, the histamin...

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Detalles Bibliográficos
Autores principales: Demarta-Gatsi, Claudia, Peronet, Roger, Smith, Leanna, Thiberge, Sabine, Ménard, Robert, Mécheri, Salaheddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567273/
https://www.ncbi.nlm.nih.gov/pubmed/28831137
http://dx.doi.org/10.1038/s41598-017-09684-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567273/
https://www.ncbi.nlm.nih.gov/pubmed/28831137
http://dx.doi.org/10.1038/s41598-017-09684-2

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