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Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite
While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity. We recently generated a Plasmodium berghei (PbNK65) parasite that lacks a secreted factor, the histamin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567273/ https://www.ncbi.nlm.nih.gov/pubmed/28831137 http://dx.doi.org/10.1038/s41598-017-09684-2 |