Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts

Cilia play important roles in cell signaling, facilitated by the unique lipid environment of a ciliary membrane containing high concentrations of sterol-rich lipid rafts. The African trypanosome Trypanosoma brucei is a single-celled eukaryote with a single cilium/flagellum. We tested whether flagell...

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Detalles Bibliográficos
Autores principales: Sharma, Aabha I., Olson, Cheryl L., Mamede, João I., Gazos-Lopes, Felipe, Epting, Conrad L., Almeida, Igor C., Engman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567337/
https://www.ncbi.nlm.nih.gov/pubmed/28831063
http://dx.doi.org/10.1038/s41598-017-08770-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567337/
https://www.ncbi.nlm.nih.gov/pubmed/28831063
http://dx.doi.org/10.1038/s41598-017-08770-9

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