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Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts
Cilia play important roles in cell signaling, facilitated by the unique lipid environment of a ciliary membrane containing high concentrations of sterol-rich lipid rafts. The African trypanosome Trypanosoma brucei is a single-celled eukaryote with a single cilium/flagellum. We tested whether flagell...
Autores principales: | Sharma, Aabha I., Olson, Cheryl L., Mamede, João I., Gazos-Lopes, Felipe, Epting, Conrad L., Almeida, Igor C., Engman, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567337/ https://www.ncbi.nlm.nih.gov/pubmed/28831063 http://dx.doi.org/10.1038/s41598-017-08770-9 |
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